2'-Deoxycytidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL002962
Members of this Pool
Members of control pools
POOL002974 N/A
Last modified: 10/Sep/2021
Results
Publication
Schmidt TT, Sharma S, Reyes GX, Gries K, Gross M, Zhao B, Yuan JH, Wade R, Chabes A, Hombauer H: A genetic screen pinpoints ribonucleotide reductase residues that sustain dNTP homeostasis and specifies a highly mutagenic type of dNTP imbalance., Nucleic Acids Res, 2019

PubMed PMCID
Value 711
Dimension pmol/108 CFU
Error (standard deviation) 106
Data presentation in publication numerical
Source
Source organism baker's yeast (Saccharomyces cerevisiae)
Taxonomy 4932
Bacterial or fungal strain derivatives of the S288c strain
Sample source strain
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions logarithmically growing cells
Treatment
Genes and Proteins
Gene name rnr1
Gene identifier 856801
Protein name Ribonucleoside-diphosphate reductase large chain 1
Protein identifier P21524
Genetic manipulation/variation mutation
Mutation in protein rnr1::kanMX4
Gene name rnr1
Gene identifier 856801
Protein name Ribonucleoside-diphosphate reductase large chain 1
Protein identifier P21524
Genetic manipulation/variation extrachromosomal expression of mutant protein
Mutation in protein G271S