DNTP011789
dCTP
dNTP Pool | |
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Pool identifier | POOL002956 |
Members of this Pool |
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Members of control pools | |
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POOL002974 | N/A |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Schmidt TT, Sharma S, Reyes GX, Gries K, Gross M, Zhao B, Yuan JH, Wade R, Chabes A, Hombauer H: A genetic screen pinpoints ribonucleotide reductase residues that sustain dNTP homeostasis and specifies a highly mutagenic type of dNTP imbalance.,
Nucleic Acids Res, 2019
PubMed PMCID |
Value | 866 | Dimension | pmol/108 CFU |
Error (standard deviation) | 34 |
Data presentation in publication | numerical |
Source | |
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Source organism |
baker's yeast
(Saccharomyces cerevisiae)
Taxonomy 4932 |
Bacterial or fungal strain | derivatives of the S288c strain |
Sample source | strain |
Compartment | whole cell |
Experiment Details | |
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Measurement type | HPLC-UV |
Extraction method | acid extraction |
Growth conditions | logarithmically growing cells |
Treatment |
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Genes and Proteins | |
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Gene name | rnr1 |
Gene identifier | 856801 |
Protein name | Ribonucleoside-diphosphate reductase large chain 1 |
Protein identifier | P21524 |
Genetic manipulation/variation | mutation |
Mutation in protein | rnr1::kanMX4 |
Gene name | rnr1 |
Gene identifier | 856801 |
Protein name | Ribonucleoside-diphosphate reductase large chain 1 |
Protein identifier | P21524 |
Genetic manipulation/variation | extrachromosomal expression of mutant protein |
Mutation in protein | F15S |