DNTP011786
dTTP
| dNTP Pool | |
|---|---|
| This entry does not belong to any pool in the database. |
| Members of control pools |
|---|
| POOL002974 |
|
Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Schmidt TT, Sharma S, Reyes GX, Gries K, Gross M, Zhao B, Yuan JH, Wade R, Chabes A, Hombauer H: A genetic screen pinpoints ribonucleotide reductase residues that sustain dNTP homeostasis and specifies a highly mutagenic type of dNTP imbalance.,
Nucleic Acids Res, 2019
PubMed PMCID |
| Value | 260 | Dimension | pmol/108 CFU |
| Error (standard deviation) | 17 |
| Data presentation in publication | numerical |
| Source | |
|---|---|
| Source organism |
baker's yeast
(Saccharomyces cerevisiae)
Taxonomy 4932 |
| Bacterial or fungal strain | derivatives of the S288c strain |
| Sample source | strain |
| Compartment | whole cell |
| Experiment Details | |
|---|---|
| Measurement type | HPLC-UV |
| Extraction method | acid extraction |
| Growth conditions | logarithmically growing cells |
| Treatment |
|---|
| Genes and Proteins | |
|---|---|
| Gene name | rnr1 |
| Gene identifier | 856801 |
| Protein name | Ribonucleoside-diphosphate reductase large chain 1 |
| Protein identifier | P21524 |
| Genetic manipulation/variation | mutation |
| Mutation in protein | rnr1::kanMX5 |
| Gene name | rnr1 |
| Gene identifier | 856801 |
| Protein name | Ribonucleoside-diphosphate reductase large chain 1 |
| Protein identifier | P21524 |
| Genetic manipulation/variation | extrachromosomal protein expression |