Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL002272
Members of this Pool
Members of control pools
POOL002257
Last modified: 10/Sep/2021
Results
Publication
Li X, Jin X, Sharma S, Liu X, Zhang J, Niu Y, Li J, Li Z, Zhang J, Cao Q, Hou W, Du LL, Liu B, Lou H: Mck1 defines a key S-phase checkpoint effector in response to various degrees of replication threats., PLoS Genet, 2019

PubMed PMCID
Value 2.98
Dimension pmol/106 cell
Error Error not provided.
Data presentation in publication diagram
Source
Source organism baker's yeast (Saccharomyces cerevisiae)
Taxonomy 4932
Bacterial or fungal strain BY4741/4742
Sample source strain
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions Cells were arrested in G1 phase, then released into S phase in the presence of 200 mM HU. Cells were collected after 0 hours after HU treatment.
Treatment
Drug/stress type drug
PubChem 3657
Applied drug hydroxyurea
Genes and Proteins
Gene name MCK1
Gene identifier 855409
Protein name Protein kinase MCK1
Protein identifier P21965
Genetic manipulation/variation mutation
Mutation in protein KO
Gene name DUN1
Gene identifier 851457
Protein name DNA damage response protein kinase DUN1
Protein identifier P39009
Genetic manipulation/variation mutation
Mutation in protein KO
Gene name CRT1
Gene identifier 856241
Protein name Copper transport protein CTR1
Protein identifier P49573
Genetic manipulation/variation mutation
Mutation in protein KO
Gene name HUG1
Gene identifier 854944
Protein name MEC1-mediated checkpoint protein HUG1
Protein identifier Q6Q5K6
Genetic manipulation/variation mutation
Mutation in protein KO