2'-Deoxycytidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL002266
Members of this Pool
Members of control pools
POOL002257
Last modified: 10/Sep/2021
Results
Publication
Li X, Jin X, Sharma S, Liu X, Zhang J, Niu Y, Li J, Li Z, Zhang J, Cao Q, Hou W, Du LL, Liu B, Lou H: Mck1 defines a key S-phase checkpoint effector in response to various degrees of replication threats., PLoS Genet, 2019

PubMed PMCID
Value 0.74
Dimension pmol/106 cell
Error Error not provided.
Data presentation in publication diagram
Source
Source organism baker's yeast (Saccharomyces cerevisiae)
Taxonomy 4932
Bacterial or fungal strain BY4741/4742
Sample source strain
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions Cells were arrested in G1 phase, then released into S phase in the presence of 200 mM HU. Cells were collected after 0 hours after HU treatment.
Treatment
Drug/stress type drug
PubChem 3657
Applied drug hydroxyurea
Genes and Proteins
Gene name MCK1
Gene identifier 855409
Protein name Protein kinase MCK1
Protein identifier P21965
Genetic manipulation/variation mutation
Mutation in protein KO
Gene name DUN1
Gene identifier 851457
Protein name DNA damage response protein kinase DUN1
Protein identifier P39009
Genetic manipulation/variation mutation
Mutation in protein KO