2'-Deoxycytidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL002251
Members of this Pool
Members of control pools
False
Last modified: 10/Sep/2021
Results
Publication
Lynx MD, LaClair DD, McKee EE: Effects of zidovudine and stavudine on mitochondrial DNA of differentiating 3T3-F442a cells are not associated with imbalanced deoxynucleotide pools., Antimicrob Agents Chemother, 2009

PubMed PMCID
Value 15
Dimension %
Error (standard error of the mean) 2
Relative compared to all dNTP
Data presentation in publication diagram
Source
Source organism mouse (Mus musculus)
Taxonomy 10090
Sample source cell line
Cell line/type as in publication 3T3F442A
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method acid extraction
Growth conditions BGM medium supplemented with newborn calf serum/fetal bovin serum/insulin; 10 days
Treatment
Drug/stress type drug
PubChem 69404750
Applied drug 3'-didehydro-3'-deoxythymidine
Treatment details/effects 1 μM d4T; polymerase gamma inhibition
Genes and Proteins
No genes or proteins manipulated.