DNTP008875
dATP
| dNTP Pool | |
|---|---|
| Pool identifier | POOL002219 |
| Members of this Pool |
|
| Members of control pools |
|---|
| N/A |
|
Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Snowdin JW, Hsiung CH, Kesterson DG, Kamath VG, McKee EE: Effects of Zidovudine Treatment on Heart mRNA Expression and Mitochondrial DNA Copy Number Associated with Alterations in Deoxynucleoside Triphosphate Composition in a Neonatal Rat Model.,
Antimicrob Agents Chemother, 2015
PubMed PMCID |
| Value | 21.2 | Dimension | % |
| Error (standard error of the mean) | 1.4 |
| Relative compared to | all NTP |
| Data presentation in publication | numerical |
| Source | |
|---|---|
| Source organism |
brown rat
(Rattus norvegicus)
Taxonomy 10116 |
| Sample source | tissue |
| Tissue type | heart |
| Compartment | whole cell |
| Experiment Details | |
|---|---|
| Measurement type | dNTP incorporation assay |
| Extraction method | acid extraction |
| Remarks to measurement type | as modified by Mathews and Wheeler |
| Growth conditions | IACUC-approved protocol, neonatal, 21 day |
| Treatment | |
|---|---|
| Drug/stress type | drug |
| PubChem | 35370 |
| Applied drug | 3′-azido-3′-thymidine |
| Treatment details/effects | DNA polymerase inhibition |
| Genes and Proteins | |
|---|---|
| No genes or proteins manipulated. | |