2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL002216
Members of this Pool
Members of control pools
POOL002210
Last modified: 10/Sep/2021
Results
Publication
Snowdin JW, Hsiung CH, Kesterson DG, Kamath VG, McKee EE: Effects of Zidovudine Treatment on Heart mRNA Expression and Mitochondrial DNA Copy Number Associated with Alterations in Deoxynucleoside Triphosphate Composition in a Neonatal Rat Model., Antimicrob Agents Chemother, 2015

PubMed PMCID
Value 57.8
Dimension %
Error (standard error of the mean) 2.8
Relative compared to all NTP
Data presentation in publication numerical
Source
Source organism brown rat (Rattus norvegicus)
Taxonomy 10116
Sample source tissue
Tissue type heart
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method acid extraction
Remarks to measurement type as modified by Mathews and Wheeler
Growth conditions IACUC-approved protocol, neonatal, 3 day
Treatment
Drug/stress type drug
PubChem 35370
Applied drug 3′-azido-3′-thymidine
Treatment details/effects DNA polymerase inhibition
Genes and Proteins
No genes or proteins manipulated.