2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL002203
Members of this Pool
Members of control pools
POOL002201
Last modified: 10/Sep/2021
Results
Publication
Barnes BJ, Izydore RA, Eakin AE, Hall IH: Mechanism of action of the antitumor agents 6-benzoyl-3,3-disubstituted-1,5-diazabicyclo[3.1.0]hexane-2,4-diones: potent inhibitors of human type II inosine 5'-monophosphate dehydrogenase., Int J Cancer, 2001

PubMed
Value 83
Dimension %
Error (SEM) 2
Relative compared to control
Data presentation in publication numerical
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
CLO Cell line name MOLT-4 cell (CLO:0007825)
Cell line/type as in publication Tmolt4
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method acid extraction
Remarks to measurement type Hunting and Henderson
Growth conditions N/A
Treatment
Drug/stress type drug
Applied drug 6-benzoyl-3-ethyl-3-(4-methylphenyl)1,5-diazabicyclo[3.1.0]hexane-2,4-diones
Treatment details/effects 100 μM drug
Genes and Proteins
No genes or proteins manipulated.