DNTP008624
dATP
dNTP Pool | |
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This entry does not belong to any pool in the database. |
Members of control pools | |
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N/A | N/A |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Herrmann A, Wittmann S, Thomas D, Shepard CN, Kim B, Ferreirós N, Gramberg T: The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation.,
Mob DNA, 2018
PubMed PMCID |
Value | 1.69 | Dimension | μM |
Error (standard deviation) | 0.46 |
Data presentation in publication | diagram |
Source | |
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Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
Sample source | cell line |
CLO Cell line name | 293T/17 cell (CLO:0001235) |
Cell line/type as in publication | 293T shSAMHD1 |
Compartment | whole cell |
Experiment Details | |
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Measurement type | LC-MS |
Extraction method | methanol |
Remarks to measurement type | Thomas et al. 2015 |
Growth conditions | FBS supplemented with 0.5 μg/ml puromycin |
Treatment | |
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Treatment details/effects | SAMHD1 silencing, overexpression of mutant |
Genes and Proteins | |
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Gene name | Samhd1 |
Gene identifier | 25939 |
Protein name | SAMHD1 |
Protein identifier | Q9Y3Z3 |
Genetic manipulation/variation | silencing |
Gene name | Samhd1 |
Gene identifier | 25939 |
Protein name | SAMHD1 |
Protein identifier | Q9Y3Z3 |
Genetic manipulation/variation | extrachromosomal expression of mutant protein |
Mutation in protein | L428S,Y432S, oligomerisation defective mutant |