DNTP008586
dTTP
| dNTP Pool | |
|---|---|
| Pool identifier | POOL002142 |
| Members of this Pool |
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| Members of control pools |
|---|
| POOL002140 |
|
Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Wittmann S, Behrendt R, Eissmann K, Volkmann B, Thomas D, Ebert T, Cribier A, Benkirane M, Hornung V, Bouzas NF, Gramberg T: Phosphorylation of murine SAMHD1 regulates its antiretroviral activity.,
Retrovirology, 2015
PubMed PMCID |
| Value | 0.521 | Dimension | μM |
| Error (standard deviation) | 0 |
| Data presentation in publication | diagram |
| Source | |
|---|---|
| Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
| Sample source | cell line |
| CLO Cell line name | THP-1 cell (CLO:0009348) |
| Cell line/type as in publication | THP-1 |
| Compartment | whole cell |
| Experiment Details | |
|---|---|
| Measurement type | LC-MS |
| Extraction method | methanol |
| Remarks to measurement type | Thomas et al. 2015 |
| Growth conditions | RPMI 1640/10% FBS |
| Treatment | |
|---|---|
| Drug/stress type | drug |
| PubChem | 27924 |
| Applied drug | PMA |
| Treatment details/effects | 50 nM; 24 hours |
| Genes and Proteins | |
|---|---|
| Gene name | Samhd1 |
| Gene identifier | 56045 |
| Protein name | SAMHD1 isoform 1 |
| Protein identifier | Q60710-1 |
| Genetic manipulation/variation | extrachromosomal expression of mutant protein |
| Mutation in protein | isoform 1, T603A |