DNTP008555
dGTP
dNTP Pool | |
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Pool identifier | POOL002134 |
Members of this Pool |
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Members of control pools | ||
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POOL002128 | POOL002130 | POOL002130 |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Garcia-Diaz B, Garone C, Barca E, Mojahed H, Gutierrez P, Pizzorno G, Tanji K, Arias-Mendoza F, Quinzii CM, Hirano M: Deoxynucleoside stress exacerbates the phenotype of a mouse model of mitochondrial neurogastrointestinal encephalopathy.,
Brain, 2014
PubMed PMCID |
Value | 1.51 | Dimension | pmol/mg protein |
Error (standard deviation) | 0.64 |
Data presentation in publication | numerical |
Source | |
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Source organism |
mouse
(Mus musculus)
Taxonomy 10090 |
Sample source | tissue |
Tissue type | brain |
Compartment | mitochondrion |
Experiment Details | |
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Measurement type | dNTP incorporation assay |
Extraction method | methanol |
Growth conditions | international standard conditions with a 12-h light, 12-h dark cycle, and sacrificed using CO2 narcosis; 16.6 mg/ml deoxythymidine and deoxyuridine in sterile drinking water; 24-month-old |
Treatment | |
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Drug/stress type | drug |
PubChem | 5789 , 13712 |
Applied drug | thymidine, deoxyuridine |
Genes and Proteins | |
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Gene name | Tymp |
Gene identifier | 72962 |
Protein name | Thymidine phosphorylase |
Protein identifier | Q99N42 |
Genetic manipulation/variation | mutation |
Mutation in protein | KO |
Gene name | Upp2 |
Gene identifier | 76654 |
Protein name | Uridine phosphorylase 2 |
Protein identifier | Q8CGR7 |
Genetic manipulation/variation | mutation |
Mutation in protein | KO |