Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL002134
Members of this Pool
Members of control pools
POOL002128 POOL002130 POOL002130
Last modified: 10/Sep/2021
Results
Publication
Garcia-Diaz B, Garone C, Barca E, Mojahed H, Gutierrez P, Pizzorno G, Tanji K, Arias-Mendoza F, Quinzii CM, Hirano M: Deoxynucleoside stress exacerbates the phenotype of a mouse model of mitochondrial neurogastrointestinal encephalopathy., Brain, 2014

PubMed PMCID
Value 6.89
Dimension pmol/mg protein
Error (standard deviation) 3.59
Data presentation in publication numerical
Source
Source organism mouse (Mus musculus)
Taxonomy 10090
Sample source tissue
Tissue type brain
Compartment mitochondrion
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Growth conditions international standard conditions with a 12-h light, 12-h dark cycle, and sacrificed using CO2 narcosis; 16.6 mg/ml deoxythymidine and deoxyuridine in sterile drinking water; 24-month-old
Treatment
Drug/stress type drug
PubChem 5789 , 13712
Applied drug thymidine, deoxyuridine
Genes and Proteins
Gene name Tymp
Gene identifier 72962
Protein name Thymidine phosphorylase
Protein identifier Q99N42
Genetic manipulation/variation mutation
Mutation in protein KO
Gene name Upp2
Gene identifier 76654
Protein name Uridine phosphorylase 2
Protein identifier Q8CGR7
Genetic manipulation/variation mutation
Mutation in protein KO