DNTP008476
dATP
| dNTP Pool | |
|---|---|
| Pool identifier | POOL002115 |
| Members of this Pool |
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| Members of control pools |
|---|
| POOL002114 |
|
Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Garone C, Garcia-Diaz B, Emmanuele V, Lopez LC, Tadesse S, Akman HO, Tanji K, Quinzii CM, Hirano M: Deoxypyrimidine monophosphate bypass therapy for thymidine kinase 2 deficiency.,
EMBO Mol Med, 2014
PubMed PMCID |
| Value | 1.51 | Dimension | pmol/mg protein |
| Error (standard deviation) | 1 |
| Data presentation in publication | numerical |
| Source | |
|---|---|
| Source organism |
mouse
(Mus musculus)
Taxonomy 10090 |
| Sample source | tissue |
| Tissue type | brain |
| Compartment | mitochondrion |
| Experiment Details | |
|---|---|
| Measurement type | dNTP incorporation assay |
| Extraction method | methanol |
| Growth conditions | Mice were housed and bred according to international standard conditions, with a 12-h light, 12-h dark cycle, and sacrificed at 13 days of age |
| Treatment |
|---|
| Genes and Proteins | |
|---|---|
| Gene name | Tk2 |
| Gene identifier | 57813 |
| Protein name | Thymidine kinase 2, mitochondrial |
| Protein identifier | Q9R088 |
| Genetic manipulation/variation | mutation |
| Mutation in protein | H126N (Tk2-/-) |