2'-Deoxyguanosine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL002079
Members of this Pool
Members of control pools
POOL002081
Last modified: 10/Sep/2021
Results
Publication
Angulo-Ibáñez M, Rovira-Clavé X, Granados-Jaén A, Downs B, Kim YC, Wang SM, Reina M, Espel E: Erk5 contributes to maintaining the balance of cellular nucleotide levels and erythropoiesis., Cell Cycle, 2015

PubMed PMCID
Value 265.5462
Dimension pmol/106 cell
Error (standard deviation) 63.8655
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Tissue type T-cell acute lymphoblastic leukemia
CLO Cell line name Jurkat, Clone E6-1 cell (CLO:0007045)
Cell line/type as in publication Jurkat E6.1
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type Mathews and Wheeler
Growth conditions normally growing cells and after 18h treatment with 1.5 mM thymidine
Treatment
Drug/stress type drug
PubChem 5789
Applied drug thymidine
Treatment details/effects MAPK7 (equals Erk5) activity has been associated with cell cycle progression
Genes and Proteins
Gene name MAPK7
Gene identifier 5598
Protein name Mitogen-activated protein kinase 7
Protein identifier Q13164
Genetic manipulation/variation silencing