DNTP008317
dTTP
dNTP Pool | |
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Pool identifier | POOL002074 |
Members of this Pool |
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Members of control pools |
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POOL002073 |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Angulo-Ibáñez M, Rovira-Clavé X, Granados-Jaén A, Downs B, Kim YC, Wang SM, Reina M, Espel E: Erk5 contributes to maintaining the balance of cellular nucleotide levels and erythropoiesis.,
Cell Cycle, 2015
PubMed PMCID |
Value | 34.0845 | Dimension | fold change |
Error (standard deviation) | 27.8873 |
Relative compared to | asynchronous control cells |
Data presentation in publication | diagram |
Source | |
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Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
Sample source | cell line |
Tissue type | T-cell acute lymphoblastic leukemia |
CLO Cell line name | Jurkat, Clone E6-1 cell (CLO:0007045) |
Cell line/type as in publication | Jurkat E6.1 |
Compartment | whole cell |
Experiment Details | |
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Measurement type | dNTP incorporation assay |
Extraction method | methanol |
Remarks to measurement type | Mathews and Wheeler |
Growth conditions | 18 h treatment with 2.5 mM thymidine; 1 μM deoxynucleosides (N: dA + dC + dG) |
Treatment | |
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Drug/stress type | drug |
PubChem | 5789 , 60961 , 6175 , 135398635 |
Applied drug | thymidine, adenosine, cytidine, guanosine |
Treatment details/effects | MAPK7 (equals Erk5) activity has been associated with cell cycle progression |
Genes and Proteins | |
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Gene name | MAPK7 |
Gene identifier | 5598 |
Protein name | Mitogen-activated protein kinase 7 |
Protein identifier | Q13164 |
Genetic manipulation/variation | silencing |