Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL002074
Members of this Pool
Members of control pools
POOL002073
Last modified: 10/Sep/2021
Results
Publication
Angulo-Ibáñez M, Rovira-Clavé X, Granados-Jaén A, Downs B, Kim YC, Wang SM, Reina M, Espel E: Erk5 contributes to maintaining the balance of cellular nucleotide levels and erythropoiesis., Cell Cycle, 2015

PubMed PMCID
Value 34.0845
Dimension fold change
Error (standard deviation) 27.8873
Relative compared to asynchronous control cells
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Tissue type T-cell acute lymphoblastic leukemia
CLO Cell line name Jurkat, Clone E6-1 cell (CLO:0007045)
Cell line/type as in publication Jurkat E6.1
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type Mathews and Wheeler
Growth conditions 18 h treatment with 2.5 mM thymidine; 1 μM deoxynucleosides (N: dA + dC + dG)
Treatment
Drug/stress type drug
PubChem 5789 , 60961 , 6175 , 135398635
Applied drug thymidine, adenosine, cytidine, guanosine
Treatment details/effects MAPK7 (equals Erk5) activity has been associated with cell cycle progression
Genes and Proteins
Gene name MAPK7
Gene identifier 5598
Protein name Mitogen-activated protein kinase 7
Protein identifier Q13164
Genetic manipulation/variation silencing