DNTP008260
dCTP
| dNTP Pool | |
|---|---|
| Pool identifier | POOL002060 |
| Members of this Pool |
|
| Members of control pools | |
|---|---|
| POOL002057 | POOL002058 |
|
|
Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Ruiz A, Pauls E, Badia R, Torres-Torronteras J, Riveira-Muñoz E, Clotet B, Martí R, Ballana E, Esté JA: Cyclin D3-dependent control of the dNTP pool and HIV-1 replication in human macrophages.,
Cell Cycle, 2015
PubMed PMCID |
| Value | 76.2295 | Dimension | pmol/106 cell |
| Error (standard deviation) | 17.7049 |
| Data presentation in publication | diagram |
| Source | |
|---|---|
| Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
| Sample source | primary cells |
| Tissue type | monocyte-derived macrophages |
| Compartment | whole cell |
| Experiment Details | |
|---|---|
| Measurement type | dNTP incorporation assay |
| Extraction method | acid extraction |
| Growth conditions | N/A |
| Treatment | |
|---|---|
| Treatment details/effects | RNA interference of Cyclin D3 blocks SAMHD1 phosphorylation and CDK2 activation |
| Genes and Proteins | |
|---|---|
| Gene name | CCND3 |
| Gene identifier | 896 |
| Protein name | G1/S-specific cyclin-D3 |
| Protein identifier | P30281 |
| Genetic manipulation/variation | silencing |