2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL002053
Members of this Pool
Members of control pools
POOL002050
Last modified: 10/Sep/2021
Results
Publication
Ballana E, Badia R, Terradas G, Torres-Torronteras J, Ruiz A, Pauls E, Riveira-Muñoz E, Clotet B, Martí R, Esté JA: SAMHD1 specifically affects the antiviral potency of thymidine analog HIV reverse transcriptase inhibitors., Antimicrob Agents Chemother, 2014

PubMed PMCID
Value 0.6705
Dimension pmol/106 cell
Error (standard deviation) 0.431
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source primary cells
Tissue type monocyte-derived macrophages
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method acid extraction
Remarks to measurement type Ferraro
Growth conditions differentiation of MDM with granulocyte-macrophage colony-stimulating factor
Treatment
Drug/stress type drug
PubChem 5789
Applied drug thymidine
Treatment details/effects dThD (1 mM) was added to the culture medium for 24 h before dNTPs were extracted and measured
Genes and Proteins
No genes or proteins manipulated.