DNTP008227
dGTP
| dNTP Pool | |
|---|---|
| Pool identifier | POOL002052 |
| Members of this Pool |
|
| Members of control pools |
|---|
| POOL002051 |
|
Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Ballana E, Badia R, Terradas G, Torres-Torronteras J, Ruiz A, Pauls E, Riveira-Muñoz E, Clotet B, Martí R, Esté JA: SAMHD1 specifically affects the antiviral potency of thymidine analog HIV reverse transcriptase inhibitors.,
Antimicrob Agents Chemother, 2014
PubMed PMCID |
| Value | 2.5628 | Dimension | pmol/106 cell |
| Error (standard deviation) | 0.5753 |
| Data presentation in publication | diagram |
| Source | |
|---|---|
| Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
| Sample source | primary cells |
| Tissue type | monocyte-derived macrophages |
| Compartment | whole cell |
| Experiment Details | |
|---|---|
| Measurement type | dNTP incorporation assay |
| Extraction method | acid extraction |
| Remarks to measurement type | Ferraro |
| Growth conditions | differentiation of MDM with granulocyte-macrophage colony-stimulating factor |
| Treatment | |
|---|---|
| Drug/stress type | stress |
| Stress type | viruls-like particle Vpx treatment |
| Treatment details/effects | transduced with VLPVpx (Virus-like particle Vpx) for 24 h; Vpx-induced degradation of SAMHD1 |
| Genes and Proteins | |
|---|---|
| No genes or proteins manipulated. | |