DNTP007651
dGTP
| dNTP Pool | |
|---|---|
| Pool identifier | POOL001893 |
| Members of this Pool |
|
Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Pontarin G, Ferraro P, Bee L, Reichard P, Bianchi V: Mammalian ribonucleotide reductase subunit p53R2 is required for mitochondrial DNA replication and DNA repair in quiescent cells.,
Proc Natl Acad Sci U S A, 2012
PubMed PMCID |
| Value | 0.18 | Dimension | pmol/106 cell |
| Error | Error not provided. |
| Data presentation in publication | diagram |
| Source | |
|---|---|
| Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
| Sample source | cell line |
| Tissue type | fibroblasts |
| CLO Cell line name | immortal myoblast cell line cell (CLO:0000057) |
| Cell line/type as in publication | Control fibroblast |
| Compartment | whole cell |
| Experiment Details | |
|---|---|
| Measurement type | dNTP incorporation assay |
| Extraction method | methanol |
| Remarks to measurement type | modified Sherman and Fyfe; Ferraro |
| Growth conditions | Irradiation with UV (24 J/m2); 3 h recovery; 2 mM HU |
| Treatment | |
|---|---|
| Drug/stress type | drug + stress |
| Stress type | UV |
| PubChem | 3657 |
| Applied drug | hydroxyurea |
| Treatment details/effects | UV (DNA damage); RNR inhibition |
| Genes and Proteins | |
|---|---|
| No genes or proteins manipulated. | |