DNTP007647
dGTP
Last modified: 10/Sep/2021
Results | |
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Publication |
Pontarin G, Ferraro P, Bee L, Reichard P, Bianchi V: Mammalian ribonucleotide reductase subunit p53R2 is required for mitochondrial DNA replication and DNA repair in quiescent cells.,
Proc Natl Acad Sci U S A, 2012
PubMed PMCID |
Value | 0.16 | Dimension | pmol/106 cell |
Error | Error not provided. |
Data presentation in publication | diagram |
Source | |
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Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
Sample source | cell line |
Tissue type | fibroblasts |
CLO Cell line name | immortal myoblast cell line cell (CLO:0000057) |
Cell line/type as in publication | Control fibroblast |
Compartment | whole cell |
Experiment Details | |
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Measurement type | dNTP incorporation assay |
Extraction method | methanol |
Remarks to measurement type | modified Sherman and Fyfe; Ferraro |
Growth conditions | Irradiation with UV (24 J/m2); 2 mM HU |
Treatment | |
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Drug/stress type | drug + stress |
Stress type | UV |
PubChem | 3657 |
Applied drug | hydroxyurea |
Treatment details/effects | UV (DNA damage); RNR inhibition |
Genes and Proteins | |
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No genes or proteins manipulated. | |