DNTP007628
dATP
| dNTP Pool | |
|---|---|
| Pool identifier | POOL001886 |
| Members of this Pool |
|
Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Pontarin G, Ferraro P, Bee L, Reichard P, Bianchi V: Mammalian ribonucleotide reductase subunit p53R2 is required for mitochondrial DNA replication and DNA repair in quiescent cells.,
Proc Natl Acad Sci U S A, 2012
PubMed PMCID |
| Value | 6.5 | Dimension | pmol/106 cell |
| Error (standard error of the mean) | 0.3 |
| Data presentation in publication | diagram |
| Source | |
|---|---|
| Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
| Sample source | cell line |
| Tissue type | fibroblasts |
| CLO Cell line name | immortal myoblast cell line cell (CLO:0000057) |
| Cell line/type as in publication | Control fibroblast |
| Compartment | whole cell |
| Experiment Details | |
|---|---|
| Measurement type | dNTP incorporation assay |
| Extraction method | methanol |
| Remarks to measurement type | modified Sherman and Fyfe; Ferraro |
| Growth conditions | pretreated with 20-50 ng/ml EtBr then 2 wk recovery period, medium composed of 5 μM AdR, CdR, and GdR |
| Treatment | |
|---|---|
| Drug/stress type | drug |
| PubChem | 14710 , 13711 , 135398592 , 13730 |
| Applied drug | Ethidium bromide;deoxycytidine, deoxyguanosine, deoxyadenosine |
| Treatment details/effects | mtDNA depletion |
| Genes and Proteins | |
|---|---|
| No genes or proteins manipulated. | |