2'-Deoxycytidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001885
Members of this Pool
Last modified: 10/Sep/2021
Results
Publication
Pontarin G, Ferraro P, Bee L, Reichard P, Bianchi V: Mammalian ribonucleotide reductase subunit p53R2 is required for mitochondrial DNA replication and DNA repair in quiescent cells., Proc Natl Acad Sci U S A, 2012

PubMed PMCID
Value 6.2
Dimension pmol/106 cell
Error (standard error of the mean) 0.18
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Tissue type fibroblasts
CLO Cell line name immortal myoblast cell line cell (CLO:0000057)
Cell line/type as in publication Control fibroblast
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type modified Sherman and Fyfe; Ferraro
Growth conditions pretreated with 20-50 ng/ml EtBr then 2 wk recovery period, medium composed of 5 μM CdR, and GdR
Treatment
Drug/stress type drug
PubChem 14710 , 13711 , 135398592
Applied drug Ethidium bromide, deoxycytidine, deoxyguanosine
Treatment details/effects mtDNA depletion
Genes and Proteins
No genes or proteins manipulated.