Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
This entry does not belong to any pool in the database.
Members of control pools
N/A
Last modified: 10/Sep/2021
Results
Publication
Rampazzo C, Fabris S, Franzolin E, Crovatto K, Frangini M, Bianchi V: Mitochondrial thymidine kinase and the enzymatic network regulating thymidine triphosphate pools in cultured human cells., J Biol Chem, 2007

PubMed
Value 27.69
Dimension %
Error Error not provided.
Relative compared to control
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Cell line/type as in publication TK1 deficient OST
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type modified Sherman and Fyfe; Ferraro
Growth conditions proliferating culture
Treatment
Drug/stress type drug
PubChem 3657
Applied drug hydroxyurea
Treatment details/effects 3 mM hydroxyurea for 60 min; Thymidine kinase (TK1) deficient, TK2 silenced cell (silenced with TK2-KF)
Genes and Proteins
Gene name TK2
Gene identifier 7084
Protein name Thymidine kinase 2, mitochondrial
Protein identifier O00142
Genetic manipulation/variation silencing