Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
This entry does not belong to any pool in the database.
Members of control pools
N/A
Last modified: 10/Sep/2021
Results
Publication
Rampazzo C, Fabris S, Franzolin E, Crovatto K, Frangini M, Bianchi V: Mitochondrial thymidine kinase and the enzymatic network regulating thymidine triphosphate pools in cultured human cells., J Biol Chem, 2007

PubMed
Value 0.4
Dimension pmol/106 cell
Error (standard deviation) 0.14
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Cell line/type as in publication TK1 deficient OST
Compartment mitochondrion
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type modified Sherman and Fyfe; Ferraro
Growth conditions 0.1 μM [3H]TdR
Treatment
Drug/stress type drug
Applied drug 3H-deoxythymidine isotope
Treatment details/effects Thymidine kinase (TK1) deficient; TK2 silenced cell
Genes and Proteins
Gene name TK2
Gene identifier 7084
Protein name Thymidine kinase 2, mitochondrial
Protein identifier O00142
Genetic manipulation/variation silencing