Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
This entry does not belong to any pool in the database.
Members of control pools
N/A
Last modified: 10/Sep/2021
Results
Publication
Rampazzo C, Fabris S, Franzolin E, Crovatto K, Frangini M, Bianchi V: Mitochondrial thymidine kinase and the enzymatic network regulating thymidine triphosphate pools in cultured human cells., J Biol Chem, 2007

PubMed
Value 0.66
Dimension pmol/106 cell
Error (standard deviation) 0.17
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
CLO Cell line name HOS cell (CLO:0003795)
Cell line/type as in publication HOS
Compartment mitochondrion
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type modified Sherman and Fyfe; Ferraro
Growth conditions 0.3 μM [3H]TdR
Treatment
Drug/stress type drug
Applied drug 3H-deoxythymidine isotope
Treatment details/effects Mitochondrial thymidine kinase (TK2) silenced, tk1 proficient
Genes and Proteins
Gene name TK2
Gene identifier 7084
Protein name Thymidine kinase 2, mitochondrial
Protein identifier O00142
Genetic manipulation/variation silencing