Results
Publication	Frangini M, Rampazzo C, Franzolin E, Lara MC, Vilà MR, Martí R, Bianchi V: Unchanged thymidine triphosphate pools and thymidine metabolism in two lines of thymidine kinase 2-mutated fibroblasts., FEBS J, 2009 PubMed
Value	1.52
Dimension	pmol/106 cell
Error	Error not provided.
Data presentation in publication	diagram

Source
Source organism	human (Homo sapiens) Taxonomy 9606
Sample source	cell line
Tissue type	fibroblasts
Cell line/type as in publication	TK2‐mutated fibroblast line, derived from a 14 year old patients with different compound heterozygous genotypes. R152G/K171del
Compartment	whole cell

Experiment Details
Measurement type	dNTP incorporation assay
Extraction method	methanol
Remarks to measurement type	modified Sherman and Fyfe; Ferraro
Growth conditions	Quiescent culture

Treatment
Treatment details/effects	Mitochondrial thymidine kinase (TK2) deficiency

Genes and Proteins
Gene name	TK2
Gene identifier	7084
Protein name	Thymidine kinase 2, mitochondrial
Protein identifier	O00142
Genetic manipulation/variation	genetic variation
Mutation in protein	heterozygous genotypes, R152G/K171del