2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001780
Members of this Pool
Members of control pools
POOL001779
Last modified: 10/Sep/2021
Results
Publication
Franzolin E, Pontarin G, Rampazzo C, Miazzi C, Ferraro P, Palumbo E, Reichard P, Bianchi V: The deoxynucleotide triphosphohydrolase SAMHD1 is a major regulator of DNA precursor pools in mammalian cells., Proc Natl Acad Sci U S A, 2013

PubMed PMCID
Value 8.2
Dimension pmol/106 cell
Error (standard error of the mean) 0.7
Data presentation in publication numerical
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Tissue type lung fibroblasts
Cell line/type as in publication lung fibroblasts (CCD34Lu)
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type modified Sherman and Fyfe; Ferraro
Growth conditions Quiescent cultures; 10 d of serum starvation
Treatment
Drug/stress type stress
Stress type starvation
Treatment details/effects Starvation
Genes and Proteins
Gene name SAMHD1
Gene identifier 25939
Protein name Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Protein identifier Q9X3Z3
Genetic manipulation/variation silencing