2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001754
Members of this Pool
Members of control pools
POOL001753
Last modified: 10/Sep/2021
Results
Publication
Back NK, Nijhuis M, Keulen W, Boucher CA, Oude Essink BO, van Kuilenburg AB, van Gennip AH, Berkhout B: Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme., EMBO J, 1996

PubMed PMCID
Value 2.5
Dimension pmol/106 cell
Error Error not provided.
Data presentation in publication numerical
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Tissue type blood
CLO Cell line name primary cultured peripheral blood mononuclear cell (CLO:0037274)
Cell line/type as in publication PBMC
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions 2-3 days with PHA (1 μg/ml) in RPMI 1640, 10% FCS, antibiotics, polybrene (5 μg/ml)
Treatment
Drug/stress type drug
Applied drug phytohemagglutinin (PHA)
Treatment details/effects activation of leukocytes
Genes and Proteins
No genes or proteins manipulated.