2'-Deoxyguanosine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001737
Members of this Pool
Members of control pools
POOL001732
Last modified: 10/Sep/2021
Results
Publication
White TE, Brandariz-Nuñez A, Valle-Casuso JC, Amie S, Nguyen LA, Kim B, Tuzova M, Diaz-Griffero F: The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation., Cell Host Microbe, 2013

PubMed PMCID
Value 34.6154
Dimension pmol/106 cell
Error Error not provided.
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Tissue type lung
CLO Cell line name U-937 cell (CLO:0009465)
Cell line/type as in publication U937 cells
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Growth conditions RPMI medium, 10% FBS, antibiotics
Treatment
Drug/stress type drug
PubChem 27924
Applied drug PMA
Genes and Proteins
Gene name SAMHD1
Gene identifier 25939
Protein name Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Protein identifier Q9Y3Z3
Genetic manipulation/variation extrachromosomal expression of mutant protein
Mutation in protein T592E