2'-Deoxycytidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001726
Members of this Pool
Members of control pools
POOL001723
Last modified: 10/Sep/2021
Results
Publication
Xie M, Yen Y, Owonikoko TK, Ramalingam SS, Khuri FR, Curran WJ, Doetsch PW, Deng X: Bcl2 induces DNA replication stress by inhibiting ribonucleotide reductase., Cancer Res, 2014

PubMed PMCID
Value 2.62
Dimension pmol/106 cell
Error (standard deviation) 0.27
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Tissue type lung
CLO Cell line name NCI-H1299 cell (CLO:0007986)
Cell line/type as in publication H1299
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions N/A
Treatment
Treatment details/effects direct suppression of RNR activity
Genes and Proteins
Gene name Bcl2
Gene identifier 12043
Protein name Apoptosis regulator Bcl-2
Protein identifier P10417
Genetic manipulation/variation extrachromosomal expression of mutant protein
Mutation in protein ΔBH2 (BH2 domain deleted)