DNTP006879
dGTP
dNTP Pool | |
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Pool identifier | POOL001725 |
Members of this Pool |
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Members of control pools |
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POOL001723 |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Xie M, Yen Y, Owonikoko TK, Ramalingam SS, Khuri FR, Curran WJ, Doetsch PW, Deng X: Bcl2 induces DNA replication stress by inhibiting ribonucleotide reductase.,
Cancer Res, 2014
PubMed PMCID |
Value | 0.27 | Dimension | pmol/106 cell |
Error (standard deviation) | 0.09 |
Data presentation in publication | diagram |
Source | |
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Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
Sample source | cell line |
Tissue type | lung |
CLO Cell line name | NCI-H1299 cell (CLO:0007986) |
Cell line/type as in publication | H1299 |
Compartment | whole cell |
Experiment Details | |
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Measurement type | HPLC-UV |
Extraction method | acid extraction |
Growth conditions | N/A |
Treatment | |
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Treatment details/effects | direct suppression of RNR activity |
Genes and Proteins | |
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Gene name | Bcl2 |
Gene identifier | 12043 |
Protein name | Apoptosis regulator Bcl-2 |
Protein identifier | P10417 |
Genetic manipulation/variation | extrachromosomal expression of mutant protein |
Mutation in protein | ΔBH1 (BH1 domain deleted) |