DNTP006814
dGTP
dNTP Pool | |
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Pool identifier | POOL001709 |
Members of this Pool |
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Members of control pools | |
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POOL001698 | POOL001704 |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Chen G, Luo Y, Warncke K, Sun Y, Yu DS, Fu H, Behera M, Ramalingam SS, Doetsch PW, Duong DM, Lammers M, Curran WJ, Deng X: Acetylation regulates ribonucleotide reductase activity and cancer cell growth.,
Nat Commun, 2019
PubMed PMCID |
Value | 5.607 | Dimension | pmol/106 cell |
Error (standard deviation) | 0.141 |
Data presentation in publication | diagram |
Source | |
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Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
Sample source | cell line |
Tissue type | lung |
CLO Cell line name | NCI-H1299 cell (CLO:0007986) |
Cell line/type as in publication | H1299 |
Compartment | whole cell |
Experiment Details | |
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Measurement type | HPLC-UV |
Extraction method | acid extraction |
Growth conditions | RPMI 1640 medium, 10% FBS |
Treatment | |
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Treatment details/effects | RRM2 silencing; mutated RRM2 overexpression |
Genes and Proteins | |
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Gene name | RRM2 |
Gene identifier | 6241 |
Protein name | Ribonucleoside-diphosphate reductase subunit M2 |
Protein identifier | P31350 |
Genetic manipulation/variation | silencing |
Gene name | RRM2 |
Gene identifier | 6241 |
Protein name | Ribonucleoside-diphosphate reductase subunit M2 |
Protein identifier | P31350 |
Genetic manipulation/variation | extrachromosomal expression of mutant protein |
Mutation in protein | K283Q |