DNTP006754
dGTP
dNTP Pool | |
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Pool identifier | POOL001694 |
Members of this Pool |
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Members of control pools |
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POOL001681 |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Coucke PA, Cottin E, Decosterd LA: Simultaneous alteration of de novo and salvage pathway to the deoxynucleoside triphosphate pool by (E)-2'-deoxy-(fluoromethylene)cytidine (FMdC) and zidovudine (AZT) results in increased radiosensitivity in vitro.,
Acta Oncol, 2007
PubMed |
Value | 3.77 | Dimension | pmol/106 cell |
Error (standard error) | Error not provided. |
Data presentation in publication | diagram |
Source | |
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Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
Sample source | cell line |
Tissue type | colon |
CLO Cell line name | WiDr cell (CLO:0009600) |
Cell line/type as in publication | WiDr cell line |
Compartment | whole cell |
Experiment Details | |
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Measurement type | HPLC-UV |
Extraction method | acid extraction |
Growth conditions | Minimum Essential Medium; 0.85 g/l NaHCO3, 10% FCS, 1% non-essential amino-acids, 2 mM L-Glutamine, 1% penicillin, 1% streptomycin, passaged twice weekly; 100 nM FMdC, 25 μM AZT |
Treatment | |
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Drug/stress type | drug |
PubChem | 35370 , 9925544 |
Applied drug | AZT, FMdC |
Genes and Proteins | |
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No genes or proteins manipulated. | |