2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001692
Members of this Pool
Members of control pools
POOL001681
Last modified: 10/Sep/2021
Results
Publication
Coucke PA, Cottin E, Decosterd LA: Simultaneous alteration of de novo and salvage pathway to the deoxynucleoside triphosphate pool by (E)-2'-deoxy-(fluoromethylene)cytidine (FMdC) and zidovudine (AZT) results in increased radiosensitivity in vitro., Acta Oncol, 2007

PubMed
Value 15.42
Dimension pmol/106 cell
Error (standard error) 1.86
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Tissue type colon
CLO Cell line name WiDr cell (CLO:0009600)
Cell line/type as in publication WiDr cell line
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions Minimum Essential Medium; 0.85 g/l NaHCO3, 10% FCS, 1% non-essential amino-acids, 2 mM L-Glutamine, 1% penicillin, 1% streptomycin, passaged twice weekly; 25 μM AZT
Treatment
Drug/stress type drug
PubChem 35370
Applied drug AZT
Genes and Proteins
No genes or proteins manipulated.