2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001684
Members of this Pool
Members of control pools
POOL001680
Last modified: 10/Sep/2021
Results
Publication
Coucke PA, Cottin E, Decosterd LA: Simultaneous alteration of de novo and salvage pathway to the deoxynucleoside triphosphate pool by (E)-2'-deoxy-(fluoromethylene)cytidine (FMdC) and zidovudine (AZT) results in increased radiosensitivity in vitro., Acta Oncol, 2007

PubMed
Value 2
Dimension pmol/106 cell
Error (standard error) 2
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Tissue type colon
CLO Cell line name WiDr cell (CLO:0009600)
Cell line/type as in publication WiDr cell line
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions Minimum Essential Medium; 0.85 g/l NaHCO3, 10% FCS, 1% non-essential amino-acids, 2 mM L-Glutamine, 1% penicillin, 1% streptomycin, passaged twice weekly; 50 nM FMdC (diagram 1)
Treatment
Drug/stress type drug
PubChem 9925544
Applied drug FMdC
Genes and Proteins
No genes or proteins manipulated.