2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001679
Members of this Pool
Members of control pools
POOL001675
Last modified: 10/Sep/2021
Results
Publication
Ahmad MF, Alam I, Huff SE, Pink J, Flanagan SA, Shewach D, Misko TA, Oleinick NL, Harte WE, Viswanathan R, Harris ME, Dealwis CG: Potent competitive inhibition of human ribonucleotide reductase by a nonnucleoside small molecule., Proc Natl Acad Sci U S A, 2017

PubMed PMCID
Value 0.63
Dimension pmol/106 cell
Error Error not provided.
Data presentation in publication numerical
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Tissue type colon
CLO Cell line name HCT 116 cell (CLO:0003665)
Cell line/type as in publication HCT116
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Growth conditions standard growth medium, RPMI 1640, 10% FBS, 2 mM glutamine, 100 U/mL penicillin, 100 μg/mL streptomycin; after growing for 24 h
Treatment
Drug/stress type drug
PubChem 3657
Applied drug Hydroxyurea
Genes and Proteins
No genes or proteins manipulated.