Thymidine-5'-triphosphate (Pubchem)
dNTP Pool
This entry does not belong to any pool in the database.
Members of control pools
N/A
Last modified: 10/Sep/2021
Results
Publication
Karlsson A, Harmenberg J: Effects of ribonucleotide reductase inhibition on pyrimidine deoxynucleotide metabolism in acyclovir-treated cells infected with herpes simplex virus type 1., Antimicrob Agents Chemother, 1988

PubMed PMCID
Value 154.3027
Dimension pmol/106 cell
Error Error not provided.
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Cell line/type as in publication human lung fibroblast (HL)
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Growth conditions 6h after HSV-1 infection; treated with 30 μM A723U and 100 μM ACV
Treatment
Drug/stress type drug + stress
Stress type viral infection
PubChem 135398513 , 5480198
Applied drug Acyclovir (ACV), 2-acetylpyridine thiosemicarbazone (A273U)
Treatment details/effects Herpes simplex virus (HSV-1) infection, two drugs
Genes and Proteins
No genes or proteins manipulated.