2'-Deoxycytidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001659
Members of this Pool
Members of control pools
POOL001656
Last modified: 10/Sep/2021
Results
Publication
Spector T, Averett DR, Nelson DJ, Lambe CU, Morrison RW Jr, St Clair MH, Furman PA: Potentiation of antiherpetic activity of acyclovir by ribonucleotide reductase inhibition., Proc Natl Acad Sci U S A, 1985

PubMed PMCID
Value 17
Dimension pmol/106 cell
Error Error not provided.
Data presentation in publication numerical
Source
Source organism African green monkey (Chlorocebus aethiops)
Taxonomy 9534
Sample source cell line
CLO Cell line name Vero cell (CLO:0009524)
Cell line/type as in publication HSV-1 virus infected Vero cells
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method acid extraction
Remarks to measurement type Garrett and Santi 1979.
Growth conditions A723U 10 μM; ACV 100 μM
Treatment
Drug/stress type drug + stress
Stress type viral infection
PubChem 54402859 , 135398513
Applied drug 2-acetylpyridine thiosemicarbazone A723U, acyclovir(ACV)
Treatment details/effects HSV-1 ribonucleotide reductase inhibition
Genes and Proteins
No genes or proteins manipulated.