DNTP006509
dATP
| dNTP Pool | |
|---|---|
| Pool identifier | POOL001632 |
| Members of this Pool |
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| Members of control pools |
|---|
| POOL001630 |
|
Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Spector T, Harrington JA, Morrison RW Jr, Lambe CU, Nelson DJ, Averett DR, Biron K, Furman PA: 2-Acetylpyridine 5-[(dimethylamino)thiocarbonyl]-thiocarbonohydrazone (A1110U), a potent inactivator of ribonucleotide reductases of herpes simplex and varicella-zoster viruses and a potentiator of acyclovir.,
Proc Natl Acad Sci U S A, 1989
PubMed PMCID |
| Value | 20 | Dimension | pmol/106 cell |
| Error | Error not provided. |
| Data presentation in publication | numerical |
| Source | |
|---|---|
| Source organism |
African green monkey
(Chlorocebus aethiops)
Taxonomy 9534 |
| Sample source | cell line |
| CLO Cell line name | Vero cell (CLO:0009524) |
| Cell line/type as in publication | HSV-1/ HSV-2 virus infected Vero cells |
| Compartment | whole cell |
| Experiment Details | |
|---|---|
| Measurement type | HPLC-UV |
| Extraction method | acid extraction |
| Growth conditions | A111OU 2 μM; ACV 0 μM |
| Treatment | |
|---|---|
| Drug/stress type | drug + stress |
| Stress type | viral infection |
| Applied drug | 2-Acetylpyridine5- [(dimethylamino)thiocarbonyl] thiocarbonohydrazone (A111OU) |
| Treatment details/effects | Ribonucleotide reductase (RNR) inhibitor (of virus) |
| Genes and Proteins | |
|---|---|
| No genes or proteins manipulated. | |