2'-Deoxyguanosine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001624
Members of this Pool
Members of control pools
POOL001623
Last modified: 10/Sep/2021
Results
Publication
Wang LM, White JC, Capizzi RL: The effect of ara-C-induced inhibition of DNA synthesis on its cellular pharmacology., Cancer Chemother Pharmacol, 1990

PubMed
Value 13.3
Dimension μmol/L cell water
Error (standard deviation) 2.6
Data presentation in publication numerical
Source
Source organism mouse (Mus musculus)
Taxonomy 10090
Sample source cell line
CLO Cell line name L5178Y cell (CLO:0007195)
Cell line/type as in publication Murine leukemia L5178Y cells
Compartment whole cell
Experiment Details
Measurement type HPLC-UV
Extraction method other organic
Remarks to measurement type Pogolotti AL, Santi DV (1982)
Growth conditions 10 μM ara-C; 0.5 h
Treatment
Drug/stress type drug
PubChem 6253
Applied drug Cytosine arabinoside (ara-C)
Treatment details/effects ara-C's predominant metabolit ara-CTP correlates with cytotoxicity
Genes and Proteins
No genes or proteins manipulated.