DNTP006449
dGTP
| dNTP Pool | |
|---|---|
| Pool identifier | POOL001617 |
| Members of this Pool |
|
| Members of control pools |
|---|
| POOL001615 |
|
Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Arnold LH, Groom HC, Kunzelmann S, Schwefel D, Caswell SJ, Ordonez P, Mann MC, Rueschenbaum S, Goldstone DC, Pennell S, Howell SA, Stoye JP, Webb M, Taylor IA, Bishop KN: Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction.,
PLoS Pathog, 2015
PubMed PMCID |
| Value | 0.881 | Dimension | pmol/106 cell |
| Error | Error not provided. |
| Data presentation in publication | diagram |
| Source | |
|---|---|
| Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
| Sample source | cell line |
| CLO Cell line name | U937(CD59+) cell (CLO:0009466) |
| Cell line/type as in publication | human myeloid leukaemia cell line U937 |
| Compartment | whole cell |
| Experiment Details | |
|---|---|
| Measurement type | dNTP incorporation assay |
| Extraction method | methanol |
| Remarks to measurement type | Sherman and Fyfe (1989); Kontoravdi (2013) |
| Growth conditions | N/A |
| Treatment | |
|---|---|
| Treatment details/effects | SAMHD1 (dGTPase) shortened mutant on plasmid |
| Genes and Proteins | |
|---|---|
| Gene name | SAMHD1 |
| Gene identifier | 25939 |
| Protein name | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 |
| Protein identifier | Q9Y3Z3 |
| Genetic manipulation/variation | extrachromosomal expression of mutant protein |
| Mutation in protein | 1-538, shortened |