2'-Deoxycytidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001616
Members of this Pool
Members of control pools
POOL001615
Last modified: 10/Sep/2021
Results
Publication
Arnold LH, Groom HC, Kunzelmann S, Schwefel D, Caswell SJ, Ordonez P, Mann MC, Rueschenbaum S, Goldstone DC, Pennell S, Howell SA, Stoye JP, Webb M, Taylor IA, Bishop KN: Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction., PLoS Pathog, 2015

PubMed PMCID
Value 0.5714
Dimension pmol/106 cell
Error Error not provided.
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
CLO Cell line name U937(CD59+) cell (CLO:0009466)
Cell line/type as in publication human myeloid leukaemia cell line U937
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type Sherman and Fyfe (1989); Kontoravdi (2013)
Growth conditions N/A
Treatment
Treatment details/effects SAMHD1 (dGTPase) on plasmid
Genes and Proteins
Gene name SAMHD1
Gene identifier 25939
Protein name Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Protein identifier Q9Y3Z3
Genetic manipulation/variation extrachromosomal protein expression