2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001475
Members of this Pool
Last modified: 10/Sep/2021
Results
Publication
Pfister SX, Markkanen E, Jiang Y, Sarkar S, Woodcock M, Orlando G, Mavrommati I, Pai CC, Zalmas LP, Drobnitzky N, Dianov GL, Verrill C, Macaulay VM, Ying S, La Thangue NB, D'Angiolella V, Ryan AJ, Humphrey TC: Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation., Cancer Cell, 2015

PubMed PMCID
Value 1
Dimension fold change
Error Error not provided.
Relative compared to control
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
Tissue type human osteosarcoma
CLO Cell line name U-2 OS cell (CLO:0009454)
Cell line/type as in publication U-2 OS
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method methanol
Remarks to measurement type Sherman and Fyfe
Growth conditions U2OS cells after control transfection with non-targeting siRNA 48 hr and DMSO treatment for 24 hr.
Treatment
Drug/stress type stress
Treatment details/effects transfection and vehicle (DMSO) control
Genes and Proteins
No genes or proteins manipulated.