DNTP005897
dTTP
| dNTP Pool | |
|---|---|
| This entry does not belong to any pool in the database. |
| Members of control pools |
|---|
| POOL001475 |
|
Last modified: 10/Sep/2021
| Results | |
|---|---|
| Publication |
Pfister SX, Markkanen E, Jiang Y, Sarkar S, Woodcock M, Orlando G, Mavrommati I, Pai CC, Zalmas LP, Drobnitzky N, Dianov GL, Verrill C, Macaulay VM, Ying S, La Thangue NB, D'Angiolella V, Ryan AJ, Humphrey TC: Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation.,
Cancer Cell, 2015
PubMed PMCID |
| Value | 0.507 | Dimension | fold change |
| Error | 0.0326 |
| Relative compared to | control |
| Data presentation in publication | diagram |
| Source | |
|---|---|
| Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
| Sample source | cell line |
| Tissue type | human osteosarcoma |
| CLO Cell line name | U-2 OS cell (CLO:0009454) |
| Cell line/type as in publication | U-2 OS |
| Compartment | whole cell |
| Experiment Details | |
|---|---|
| Measurement type | dNTP incorporation assay |
| Extraction method | methanol |
| Remarks to measurement type | Sherman and Fyfe |
| Growth conditions | U2OS cells stably expressing an empty vector, transfected with control siRNA (48 hr) prior to treatment with DMSO (24 hr). |
| Treatment | |
|---|---|
| Drug/stress type | drug |
| PubChem | 24856436 |
| Applied drug | AZD1775 |
| Treatment details/effects | drug treatment; silencing control |
| Genes and Proteins | |
|---|---|
| No genes or proteins manipulated. | |