2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
This entry does not belong to any pool in the database.
Members of control pools
N/A
Last modified: 10/Sep/2021
Results
Publication
Ismail A, Van Groeningen CJ, Hardcastle A, Ren Q, Aherne GW, Geoffroy F, Allegra CJ, Grem JL: Modulation of fluorouracil cytotoxicity by interferon-alpha and -gamma., Mol Pharmacol, 1998

PubMed
Value 273
Dimension pmol/106 cell
Error (standard error) 56
Data presentation in publication numerical
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source cell line
CLO Cell line name HT-29 cell (CLO:0004283)
Cell line/type as in publication HT-29
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method acid extraction
Remarks to measurement type Sherman and Fyfe
Growth conditions RPMI 1640 with 8% FBS and 2 mM glutamine; cells were treated with 1 mM 5-fluorouracil for 24 hours
Treatment
Drug/stress type drug
PubChem 3385
Applied drug 5-fluorouracil
Treatment details/effects cells were treated with 5-fluorouracil, a nucleobase analogue antineoplastic agent
Genes and Proteins
No genes or proteins manipulated.