DNTP005823
dUTP
dNTP Pool | |
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This entry does not belong to any pool in the database. |
Members of control pools |
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N/A |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Ismail A, Van Groeningen CJ, Hardcastle A, Ren Q, Aherne GW, Geoffroy F, Allegra CJ, Grem JL: Modulation of fluorouracil cytotoxicity by interferon-alpha and -gamma.,
Mol Pharmacol, 1998
PubMed |
Value | 4.7 | Dimension | pmol/106 cell |
Error (standard error) | 1.36 |
Data presentation in publication | diagram |
Source | |
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Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
Sample source | cell line |
CLO Cell line name | HT-29 cell (CLO:0004283) |
Cell line/type as in publication | HT-29 |
Compartment | whole cell |
Experiment Details | |
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Measurement type | Radioimmune assay |
Extraction method | acid extraction |
Growth conditions | RPMI 1640 with 8% FBS and 2 mM glutamine; cells were treated with 500 units/ml interferon-alpha 2a and 10 units/ml interferon-gamma 1b for 48 hours, 1 mM 5-fluorouracil was added for the final 24 hr |
Treatment | |
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Drug/stress type | drug |
PubChem | 3385 |
Applied drug | 5-fluorouracil |
Treatment details/effects | cells were treated with interferon alpha and gamma regulatory proteins, and 5-fluorouracil, a nucleobase analogue antineoplastic agent |
Genes and Proteins | |
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No genes or proteins manipulated. | |