DNTP005797
dATP
dNTP Pool | |
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This entry does not belong to any pool in the database. |
Members of control pools |
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N/A |
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Last modified: 10/Sep/2021
Results | |
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Publication |
Durand-Gasselin L, Da Silva D, Benech H, Pruvost A, Grassi J: Evidence and possible consequences of the phosphorylation of nucleoside reverse transcriptase inhibitors in human red blood cells.,
Antimicrob Agents Chemother, 2007
PubMed PMCID |
Value | 60.69 | Dimension | % |
Error (standard deviation) | 2.32 |
Relative compared to | control |
Data presentation in publication | diagram |
Source | |
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Source organism |
human
(Homo sapiens)
Taxonomy 9606 |
Sample source | primary cells |
Cell line/type as in publication | peripheral blood mononuclear cells (PBMC) |
Compartment | whole cell |
Experiment Details | |
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Measurement type | LC-MS |
Extraction method | methanol |
Growth conditions | venous blood from HIV infected patients, who were receiving antiretroviral therapy; whole blood was incubated with 5 μM tenofovir and 5 μM lamivudine for 24 h; PBMC pellets were artificially contaminated with 100% red blood cells isolated from the same blood after incubation, then sample was treated with red blood cell lysis solution |
Treatment | |
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Drug/stress type | drug |
PubChem | 464205 , 60825 |
Applied drug | tenofovir, lamivudine |
Genes and Proteins | |
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No genes or proteins manipulated. | |