2'-Deoxyadenosine 5'-triphosphate (Pubchem)
dNTP Pool
This entry does not belong to any pool in the database.
Members of control pools
N/A
Last modified: 10/Sep/2021
Results
Publication
Durand-Gasselin L, Da Silva D, Benech H, Pruvost A, Grassi J: Evidence and possible consequences of the phosphorylation of nucleoside reverse transcriptase inhibitors in human red blood cells., Antimicrob Agents Chemother, 2007

PubMed PMCID
Value 288.44
Dimension %
Error (standard deviation) 7.51
Relative compared to control
Data presentation in publication diagram
Source
Source organism human (Homo sapiens)
Taxonomy 9606
Sample source primary cells
Cell line/type as in publication peripheral blood mononuclear cells (PBMC)
Compartment whole cell
Experiment Details
Measurement type LC-MS
Extraction method methanol
Growth conditions venous blood from HIV infected patients, who were receiving antiretroviral therapy; whole blood was incubated with 5 μM tenofovir and 5 μM lamivudine for 24 h; PBMC pellets were artificially contaminated with 200% red blood cells isolated from the same blood after incubation
Treatment
Drug/stress type drug
PubChem 464205 , 60825
Applied drug tenofovir, lamivudine
Genes and Proteins
No genes or proteins manipulated.