2'-Deoxycytidine-5'-triphosphate (Pubchem)
dNTP Pool
Pool identifier POOL001441
Members of this Pool
Members of control pools
POOL001437 POOL001436
Last modified: 10/Sep/2021
Results
Publication
Ingraham HA, Dickey L, Goulian M: DNA fragmentation and cytotoxicity from increased cellular deoxyuridylate., Biochemistry, 1986

PubMed
Value 102
Dimension nmol/mL cell volume
Error Error not provided.
Data presentation in publication numerical
Source
Source organism Chinese hamster (Cricetulus griseus)
Taxonomy 10029
Sample source cell line
Cell line/type as in publication CCL39
Compartment whole cell
Experiment Details
Measurement type dNTP incorporation assay
Extraction method acid extraction
Remarks to measurement type Solter and Handschumacher
Growth conditions modified Eagle's medium with 10% FBS, 100 μM hypoxanthine, 10 μM methotrexate, 5 μM thymidine and 10 μM deoxyuridine
Treatment
Drug/stress type drug
PubChem 126941
Applied drug methotrexate
Treatment details/effects Dihydrofolate reductase inhibition
Genes and Proteins
No genes or proteins manipulated.